Opekiska Lock and Dam is a navigational lock and gated dam on the Monongahela River at Lowsville, West Virginia. It is part of a series of dams that canalizes the Monongahela to a depth of at least 9 feet (2.7 m) for its entire length from Fairmont, West Virginia to Pittsburgh, Pennsylvania. It is maintained by the U.S. Army Corps of Engineers' Pittsburgh District.